Mariana Cruz Manzano, MD
Dermatology · Caguas, PRNPI 1760821565
Payments from drug & device makers
What this record shows
This record is dominated by food and beverage: $1,556 of the $1,917 with a category attached, or 81.1%. 11 manufacturers reported payments, led by Johnson & Johnson at 30.9% of the total. That places this record below the midpoint for dermatology clinicians in PR, where the typical reported total is $1,906.
Across 69 payments — averaging $27.78 each. Meals, travel, consulting and speaking fees, gifts and royalties reported by drug and device makers.
- Johnson & Johnson$592
- AbbVie$381
- Sanofi$339
- Eli Lilly Export S.A. Puerto Rico Branch$208
- Amgen$105
- Sanofi-aventis U.S. LLC$100
- plus $193 from 5 others
What the payments were for
- Food & beverage$1,55681%
- Education$36119%
Most of this is food and beverage — typically meals provided during product presentations at a clinic or hospital. Nationally that is the single largest category of reported payments by count.
General payments by program year
Who reported the general payments
Companies are grouped under their corporate parent — a single manufacturer often files under several CMS reporting entities. Research and ownership payments are counted separately and are not in this table.
| Company | Payments | Total |
|---|---|---|
| Johnson & Johnson(2 entities) | 16 | $592 |
| AbbVie | 17 | $381 |
| Sanofi | 11 | $339 |
| Eli Lilly Export S.A. Puerto Rico Branch | 9 | $208 |
| Amgen | 5 | $105 |
| Sanofi-aventis U.S. LLC | 1 | $100 |
| PBG Puerto Rico LLC | 3 | $63 |
| Revance Therapeutics, Inc. | 2 | $58 |
| Pfizer | 2 | $31 |
| E.r. Squibb & Sons, L.L.C. | 2 | $27 |
| Galderma Laboratories, L.p. | 1 | $15 |
What the payments were tied to
Products named in the reported payments. Only payments of $100 or more are attributed here — the typical reported payment nationally is a meal worth about $16, and listing those product-by-product would be noise.
- DUPIXENT$109
How this compares
$1,917 in reported general payments places this provider in the 50th percentile of 108 dermatology providers in Puerto Rico.
Medicare billing
What this is not: this is the amount Original Medicare Part B allowed for services this provider billed in 2024. It is not their income. It excludes Medicare Advantage — now more than half of all Medicare enrollment — along with Medicaid and all commercial insurance, and it is gross practice revenue before staff, rent, supplies and malpractice premiums. CMS also suppresses any figure covering ten or fewer patients, so low-volume providers appear smaller than they are.
Most prescribed under Part D
| Drug | Claims | Cost to plans & patients |
|---|---|---|
| Skyrizi PenRisankizumab-Rzaa | 26 | $523,787 |
| OtezlaApremilast | 20 | $96,803 |
| Dupixent PenDupilumab | 14 | $53,304 |
| Clobetasol Propionate | 407 | $25,644 |
| Betamethasone Dipropionate | 261 | $12,086 |
| Ketoconazole | 514 | $11,457 |
| Calcipotriene | 81 | $9,458 |
| Acitretin | 11 | $8,297 |
| Ciclopirox | 192 | $7,263 |
| Tacrolimus | 42 | $4,500 |
| Betamethasone Diprop AugmentedBetamethasone/Propylene Glyc | 111 | $3,934 |
| Metronidazole | 48 | $3,199 |
| Mometasone Furoate | 123 | $3,176 |
| Betamethasone Valerate | 70 | $2,747 |
| Triamcinolone Acetonide | 283 | $2,696 |
Paid to pharmacies, not to this prescriber.
Companies that both paid and supply prescribed drugs
These companies both reported payments to this provider and make drugs the provider prescribed under Medicare Part D in 2024. For most specialties this overlap is expected — a cardiologist who is paid by a cardiology drugmaker also treats heart disease. It is shown so the reader can see it, not because it implies anything on its own.
| Company | Paid to this provider | Part D cost of their drugs |
|---|---|---|
| AmgenOtezla | $105 | $96,80320 claims |
Reading this fairly. The Part D column is what drug plans and patients paid pharmacies — this provider received none of it, and it reflects how many patients they treat and what those drugs cost. Against peers, this provider's reported payments sit in the 50th percentile of 108 dermatology providers in Puerto Rico.
Other dermatology in Caguas
- Samuel SanchezCaguas$25K
- Julian Barrera LlauradorCaguas$6K
- Erika Watts OquendoCaguas$2K
- Rachelle SeijoCaguas$2K
- Nicole CarvajalCaguas$2K
- Luz Figueroa GuzmanCaguas$2K
- Jose Gonzalez ChavezSan Juan$248K
- Rafael Martin GarciaSan Juan$199K
- Noelani Gonzalez-OrtizSan Juan$154K
- Alma Cruz SantanaCarolina$74K
Where these figures come from
- Payments: CMS Open Payments, program years 2019–2025 (publication P06302026_06032026).
- Billing: Medicare Physician & Other Practitioners, data year 2024. Original Medicare Part B only.
- Identity: NPPES NPI Registry, July 2026.